Astaroth is the main villain of the Ghosts 'n Goblins games. He almost always appears as a large ferocious beast with horns. A demonic face is located in the middle of his torso, which contains within it the means of his defeat.
- Ghosts 'n Goblins: He is the evil and merciless ruler of the Makai. Extremely resistant to pain, he can shoot fireballs from both of his mouths.
- Ghouls 'n Ghosts: Having lost the throne of the Makai after his first defeat, he now watches Lucifer's keep. Instead of fireballs, this time he will attack the player with his long-ranged fiery breath from both of his mouths. The player must face him two times in a row, and the second time he divides himself and corners Arthur if one of his forms is not defeated quickly enough.
- Super Ghouls 'n Ghosts: This large beast shoots laser beams and a trail of fireballs from its two mouths. He also likes to stomp on Arthur if given the chance. He will battle Arthur two times. When he is finally slain the first time, he is resurrected as Nebiroth, an undead version of his former self.
- Ultimate Ghosts 'n Goblins: He is back for the final showdown! In this entry, he is called Dark Astaroth and has large black wings.
- Gargoyle's Quest II: He is known as King Morock.
- In some older English localizations, he is often called Lucifer. Confusingly, Lucifer is actually the final boss of Ghouls 'n Ghosts.