Below is a list of Special Weapons obtained by defeating the Robot Masters in the game Mega Man 8, how Mega Man can use them to his advantage and the Robot Master/boss who is the most vulnerable to them.
| Special Weapons | ||||
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| Name | Astro Crush | |||
| Robot Master | Astro Man | |||
| Abilities | Creates a meteor storm that hits all enemies on the screen, and Mega Man is invincible for a short time when using it. | |||
| Against | Aqua Man | |||
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| Name | Flame Sword | |||
| Robot Master | Sword Man | |||
| Abilities | A close-range weapon capable of igniting obstacles and enemies. | |||
| Against | Search Man, Frost Man | |||
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| Name | Flash Bomb | |||
| Robot Master | Grenade Man | |||
| Abilities | When it hits a wall or an enemy, its explosion stays on the screen for a while, causing multiple hits. Can also light dark areas. | |||
| Against | Frost Man | |||
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| Name | Homing Sniper | |||
| Robot Master | Search Man | |||
| Abilities | A crosshair appears on an enemy it's locked on and a missile shoots out to it. Chargeable. | |||
| Against | Astro Man | |||
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| Name | Ice Wave | |||
| Robot Master | Frost Man | |||
| Abilities | Sends a flow of ice along the floor until it hits a wall. It can freeze enemies and even damage some of them. | |||
| Against | Tengu Man | |||
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| Name | Thunder Claw | |||
| Robot Master | Clown Man | |||
| Abilities | Shoots out a stretching beam of electricity which Mega Man can attach to hooks and swing from them. | |||
| Against | Grenade Man | |||
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| Name | Tornado Hold | |||
| Robot Master | Tengu Man | |||
| Abilities | Drops a fan on the ground that creates a tornado that can trap and/or damage enemies. | |||
| Against | Clown Man | |||
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| Name | Water Balloon | |||
| Robot Master | Aqua Man | |||
| Abilities | Sends a sphere of water at a low arc. | |||
| Against | Sword Man | |||